• Prepare the spice blend: In a small bowl, combine the garlic powder, onion powder, dried oregano, sweet paprika, and salt. Set aside.
• Mix the oil and butter: In another small bowl, combine the olive oil and melted butter. Set aside.
• Prep the salmon: Pat the salmon dry with a paper towel.

For Skin-on Salmon

• Start in a cold pan: Add 2 tablespoons of the olive oil–butter mixture to a cold skillet. Place the salmon skin-side down, then turn the heat to medium-high.
• Cook and press: For the first 2 minutes, press down on the salmon with a spatula to keep the skin flat against the pan. Continue cooking for an additional 4 minutes.
• Season and flip: Drizzle the remaining butter mixture over the top and sprinkle with the spice blend. Carefully flip the salmon.
• Finish cooking: Cook for another 3 minutes, or until the salmon reaches your desired doneness.

For Skinless Salmon:

• Heat the pan: Add 1 tablespoon of the butter–olive oil mixture to a skillet over medium-high heat.
• Season the salmon: Brush both sides of the salmon with the remaining butter mixture, then coat evenly with the spice blend.
• Cook the first side: Once the pan is hot, add the salmon and cook without moving for 3–5 minutes, until blackened on the bottom.
• Flip and finish: Carefully flip and cook for another 3–5 minutes, or until the salmon reaches your desired doneness.